Tests of varying scientific nature and credibility are widely alleged to have the ability to differentiate between good and bad organic trace minerals (OTMs). The basic parameters that can be analyzed include mineral percentage, nitrogen-to-mineral ratio, percent of bound mineral, molecular weight, bioavailability and stability. While some of these analyses can provide meaningful and valuable information about defined or individual products, understanding the limitations of these tests is critical if they are to be successfully applied in the assessment of OTMs.

Mineral percentage

Accurate quantification of the total mineral content of OTMs is routinely used by all manufacturers, and cost comparisons between OTMs will consider this when calculating their relative value. Total mineral content, however, gives no information regarding OTM bioavailability and, as such, is limited in terms of calculating the true relative value of a product.

Nitrogen-to-metal ratio

Calculating the molar ratio of nitrogen to metal can be a useful way to assess glycine-based chelates. When assessing more complex products, such as proteinates, the nitrogen-to-mineral ratio will not give an accurate reflection of the true potential for mineral bonding. More complex amino acids can bind metal atoms through their side chains via sulfur and oxygen atoms. As there is no involvement of nitrogen in this side chain bonding, it is possible to underestimate the potential for binding by only considering the nitrogen-to mineral ratio. The nitrogen content of various products can also be artificially inflated, giving the false impression of a product with high nitrogen-to-mineral ratio.

Solubility

It is often asserted that an OTM must be soluble to be bioavailable, but many peer-reviewed publications have shown that insoluble OTMs have the potential to be more bioavailable than their soluble counterparts. An evaluation of OTM solubility will be of little benefit unless one considers the effects of the digestive processes and the changing pH environment within the GI tract.

Molecular weight

Numerous claims have been made about comparing OTMs based on size, and these claims erroneously indicate that a smaller-sized bonding group creates a more stable and more bioavailable OTM. Correlating the molecular weight of an OTM with its stability constant indicates quite clearly that, rather than size being of critical importance in generating a stable OTM, the type of bonding group is of far greater significance.  

Bioavailability

In vitro lab-based assays, which attempt to assess bioavailability, have been developed, making use of cell culture-based assay systems that can determine the transfer and uptake of minerals across cellular membranes. These techniques, however, can’t accurately reflect the influence of digestion on the OTM. As such, their value when comparing different products is limited.

Stability

When we talk about the stability of OTMs, we are referring to the bond strength that exists between the bonding group and the mineral; the greater the bond strength, the more stable the product. Polarography can be used to assess the bond strength of OTMs — but polarography is only suitable to test materials in solution and can only assess the soluble fraction of organic mineral products. OTMs are increasingly solubilised as a result of the in vivo conditions of the GI tract, so the results of the polarographic tests alone should be interpreted with caution.

Percent of bound mineral

Historically, determining the percent of bound mineral required utilizing filtration through a low-molecular-weight membrane. The mineral retained behind the filter was assumed to be bound, while the mineral in the filtrate (solution) was assumed to be unbound. Such methods, however, are subject to manipulation, as changing the pH of the buffer can cause precipitation and lead to false estimates of the true bound mineral percentage.

The only validated assays that fully quantitate the bound mineral level of an OTM utilize techniques known as ATR-FTIR (attenuated total reflectance Fourier transform infrared) and PXRD (power X-ray diffraction) and were developed by researchers at Alltech’s European Bioscience Centre.

The first assay uses a form of infrared (IR) spectroscopy to measure the bound mineral percentage, whereas the second assay uses a form of crystallography to measure the unbound mineral level. These two assays are complementary to each other, and both are peer-reviewed and published. In the case of the IR assay, this was independently validated and verified by the Central Reference Laboratory (CRL), which reports directly to the European Food Safety Authority (EFSA).

Conclusion

While simple tests based on mineral percentage, nitrogen-to-mineral ratio, molecular weight, bioavailability and stability are used by different manufacturers, these tests only provide limited information about individual products and are not suitable for comparing different classes of product. If products will continue to be compared through these tests, understanding their limitations is critical.

The only validated assays to assess mineral chelation are based on the use of techniques known as ATR-FTIR and PXRD and were developed and validated by researchers at Alltech’s European Bioscience Centre. 

Click here for more information on Alltech's Mineral Management program. 

References:

Byrne, L. A., Hynes, M.J., Connolly, C.D. and Murphy, R.A. (2011) 

Analytical determination of apparent stability constants using a copper ion selective electrode. Journal of Inorganic Biochemistry, 105(12):1656-1661.

Byrne, L.A. (2010) Analytical assessment of peptide-metal interactions and subsequent stability. Ph.D. Thesis. Dept. of Biology, National University of Ireland, Maynooth, Ireland.

Cantwell C, Byrne L, Connolly C, Hynes MJ, McArdle P, Murphy RA. (2017)

Quantitative assessment of copper proteinates used as animal feed additives using ATR-FTIR spectroscopy and powder X-ray diffraction (PXRD) analysis. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2017 Aug;34(8):1344-1352.

Murphy R.A. (2018) Organic Trace Minerals: Optimised Stability Enhances Bioavailability International Animal Health Journal Vol 5 (2) 28-32

Murphy, R.A. (2018) Minerals, Meals and Molecular Malnutrition: How Mineral Form Can Impact Feed Quality and Cellular Health. International Animal Health Journal Vol 5 (1) 42-46

Murphy R.A. (2015) OTM bond strength, relative stability

Feedstuffs July

Murphy, R.A. (2010) Drilling into mineral analysis – structure and stability explained. All about feed Vol 1 (4) 21-23

Murphy, R., (2009).  Chelates: Clarity in the confusion. Feed international January/February 22-24.

Article reposted with permission from CRYSTALYX^®.

For many, fall calving lies in the near future. Have you considered whether your cowherd’s summer mineral program is up to par? Implementing a proper mineral program is essential, as it can help determine the best way to maintain optimal reproduction with early conception rates while also boosting calf health and growth. We only get one calf per cow per year, so if there are any missteps in meeting our cow reproduction and calf growth goals, it will be a long time before corrections or improvements can be made.

During the late summer and into the early fall, forage quality is declining as the cow’s requirements are increasing for fall calving. Delivering minerals during this time is crucial in order to produce a healthy calf and ensure that the cow has what she needs to combat any stressors and to rebreed in time. For spring-calving herds, the period when calves are getting pulled and weaned is when the cow’s nutrient requirements are lowest; however, a proper mineral program is still necessary to provide for both the cow and her developing calf throughout the year.

Summer mineral programs

When considering a mineral program, bags and mineral feeders likely spring to mind, as these options have historically been used often and to good results. You may want to consider, however, thinking a little more deeply about some other summer mineral options that could help you stay on top of your herd’s nutrition program without the fuss and potential losses associated with dry granular mineral delivery. For instance, compared to bagged minerals, there are many inherent benefits provided by low-moisture blocks like CRYSTALYX low-moisture block mineral supplements.

Two of the biggest advantages of CRYSTALYX mineral supplements are their palatability and the uniformity of intake they ensure across all cattle within a pasture. Our research has demonstrated that more than 90% of cattle will frequent a CRYSTALYX mineral supplement, versus the roughly 60% of cattle that frequent an area where bagged minerals are available.

It is an undisputable fact that if your cows don’t eat the vitamin/mineral supplement you provide, they will not be able to capitalize on the additional nutritional benefits offered by that supplement. Reaching 30% more cattle within a herd helps ensure that nearly all of your cattle are receiving the added nutrients that encourage optimal performance. This is, without a doubt, the main reason that producers look to CRYSTALYX to help efficiently deliver their summer minerals.

That is certainly not the end of the list of benefits CRYSTALYX supplements can provide. There are a great deal of manufacturing processes and ingredients involved in creating a weatherized, bagged mineral that won’t blow away in the wind, wash down the creek in the rain or simply turn to stone after a downpour. What better weatherproof mineral could you offer than what already comes with CRYSTALYX?

CRYSTALYX low-moisture blocks are unaffected by wind or rain; cattle will simply slurp down any moisture that accumulates on the surface. And what could be more appealing to cows than a good-old consumption-regulated, low-moisture molasses block? There are a host of different intake limiters, encouragers and regulators associated with bagged vitamin/mineral products — but when cows actually want to consume your vitamin/mineral supplement presented in block form, they become unnecessary, as the nutrition is encased in a highly palatable, uniformly blended, dehydrated molasses block that keeps intake in check.

Let’s not forget how the minerals and vitamins are encased in a dehydrated molasses matrix, which is hugely beneficial, as it separates — and virtually eliminates — the reactivity that often exists between minerals and vitamins. Our observations have consistently revealed almost zero vitamin degradation with CRYSTALYX products when measured for up to and even beyond one year. This is certainly not the case with bagged minerals; harmful oxidative reactions begin to take place once the ingredients are mixed together, eventually destroying the vitamin potency.

One thing to remember when managing intake with CRYSTALYX mineral formulations is that the head count per container must be scaled up compared to the protein formulations. Follow the label recommendations, but generally, more cows per container — such as 40 to 60 head per barrel — should be considered to arrive at a 4-ounce intake. Compare this to our typical recommendation of 20 to 30 head for protein products, which are typically consumed in the 0.5- to 1-pound daily intake range.

Mineral feeders: Who needs them?

Upfront equipment costs are one thing, but continued maintenance expenses are seemingly never-ending. Bulls are always looking for some sort of recreational equipment to rough up, and feeders are common targets. There are plenty of creative feeding methods for providing loose minerals. Some producers make it sort of a puzzle that cows must figure out in order to access the mineral — which can really make you wonder just how many cows are actually courageous or creative enough to put their heads into these feeding stations. CRYSTALYX supplements come with their own container — and if you request that they be provided in the degradable BioBarrel^®, you don’t even have to go out and pick them up; they just degrade away into the environment. It doesn’t get much easier or more environmentally responsible than that.

A CRYSTALYX mineral program to fit your needs

If you’re not yet convinced to take a fresh look at how you provide vitamin and mineral supplementation to your cow herd, stop by your nearest CRYSTALYX dealer to get the full scoop on how our mineral products can add value to both your cow herd and calf crop, thereby increasing your operational returns. When technology arrives that can take us light-years ahead, we should adopt it and make it the norm. Providing proper vitamin and mineral delivery on-pasture is as easy as finding the right CRYSTALYX product to meets your cows’ needs.

I want to learn more about improving nutrition for my cattle.

Article reposted with permission from CRYSTALYX^®.

Fetal programming, also known as “developmental programming,” has been a hot topic for a number of years now. When we consider fetal programming from a nutritional perspective, we think of the lasting impacts gestational maternal nutrition can have on calves. I have often heard farmers and ranchers say, “If you take care of your cows, they will take care of you,” and this certainly rings true in this instance.

We often think about fetal programming during late gestation. Naturally, we begin thinking about the upcoming calving season after last year’s calves are weaned. We know that nearly 70% of fetal growth occurs during the last trimester — but for a calf to be able to grow at an exponential rate during that time and remain healthy during its postnatal life (which will correlate to increased performance and profitability), giving it a prenatal head start during early gestation will be most beneficial.

Unfortunately, however, maintaining a focus on nutrition often gets put on the back burner during early pregnancy. After all, there’s a lot to keep up with in the summer! Cows and bulls are turned out on grass, we’re busy with breeding, and we get caught up baling forages to feed cows with in the winter. You may think that the cows are doing just fine nutritionally, but they — and their developing calves — might be missing out on more than you realize.

Get with the (fetal) program

Although fetal nutrient requirements are minimal during early and mid-gestation (making up less than 12 percent of the cow’s total requirements), from a production standpoint, gestation begins exactly when the cow’s nutrient requirements are greatest, due to the increased demands of lactation.

The placenta and many vital fetal organs develop during early gestation, which continues up to approximately day 90 in cattle. The placenta is responsible for conveying all of the nutrients and oxygen to the growing and developing calf; it also removes waste products. The placental formation in early gestation is crucial for optimizing vascularity and nutrient transfer to maximize blood flow, which is important for the calf’s overall growth. Research measuring the placenta and studying its effects on gestation has shown that nutrient restriction during early gestation can continue to negatively impact the animal throughout the entirety of gestation, even if the cow is provided with their nutritional requirements during late gestation. The impact of restricting nutrients early on includes smaller placenta sizes and decreased blood flow to the calf (Vonnahme et al., 2007, 2013).

Along with the placenta, the calf’s organs also develop during early pregnancy. Cells are dividing at this time, and this early formation of the organ system is crucial for the calf once it is born. These developing organs — such as the lungs and the gastrointestinal tract — are necessary not only for survival, but also for reproduction and the growth of muscle cells. Studies show that nutrient restriction to the cow during this phase can negatively impact organ development and productivity later in the calf’s life; in other words, restricting the cow also restricts the calf’s genetic potential. Genetic selection happens when the producer is making mating decisions, but you can program the calf during gestation to help increase the profitability of your genetics by providing ideal growing conditions. You have worked too hard with too many generations of your herd to take a step back in calf performance potential by not providing the necessary nutrients during gestation.

In order for these vital organs to develop properly — and to maximize your calves’ genetic potential — make sure your gestating cows don’t run short of critical nutrients, like macro and trace minerals, vitamins and protein. These nutrients generally must be delivered to the cow in forms that go beyond simple pasture forages. An easy way to ensure that these nutrients are provided is through a self-fed supplement, such as CRYSTALYX^® Brand Supplements, which are formulated with Alltech’s organic Bioplex^®  trace minerals.

A simple way to provide supplementation

As we wrap up the breeding season and get closer to the fall season, pasture conditions and forage quality often begin to decline. We should keep in mind that this can be a stressful time of year not only for us, but also for our animals. Consider what your cows are consuming and think about whether they might benefit from supplementation, beginning now and continuing through early gestation and beyond. CRYSTALYX Brand Supplements are a simple solution to make sure that your cows are consuming the nutrients that both they and the calves by their side and in utero need. 

Let’s face it: the summer months are a busy time for us all. Whether you are getting things done around the farm or ranch, catching up with friends and family, or just trying to stay cool, your cows out on pasture may not be getting as much attention as they need. After all, they can’t take any time off during the critical period of early gestation. Fortunately, you can minimize time and labor — and give yourself peace of mind — by putting out a self-fed CRYSTALYX barrel, which will be available to your cows around the clock. Your cows will essentially be taking care of themselves, and by raising better-performing, more profitable calves, ultimately, they will also be taking care of you.

_{Fowden, A. L., D. A. Giussani, and A. J. Forhead. 2006. Intrauterine programming of physiological systems: causes and consequences. Physiology (Bethesda) 21: 29-37.}

_{Vonnahme, K. A., M. J. Zhu, P. P. Borowicz, T. W. Geary, B. W. Hess, L. P. Reynolds, J. S. Caton, J. W. Means, and S. P. Ford. 2007. Effect of early gestational undernutrition on angiogenic factor expression and vascularity in the bovine placentome. J. Anim. Sci. 85: 2464-2472.}

_{Vonnahme, K., C. Lemley, P. Shukla, and S. O’Rourke. 2013. 2011 and 2012. Early Careers Achievement Awards: Placental programming: How the maternal environment can impact placental function. J. Anim. Sci. 91: 2467-2480.}

I want to learn more about nutrition for my beef cattle.

The following is an excerpt from an article by Solutions Deployment Team Manager Dr. Jules Taylor-Pickard on Pig Progress.

Times are long gone when supplying minerals to pigs was one-size-fits-all. Sows have different demands depending on their parity, size and litter size. Supplying the correct amounts will enhance sow performance — and will provide benefits for her piglets, too.

Minerals are important for maintaining the body and ensuring animal performance. In breeding sows, certain minerals are needed for successful conception and parturition. Chromium influences follicle-stimulating and luteinizing hormones and is also needed to produce insulin, which affects progesterone production. Both hormones are required for regulating ovulation and have a direct impact on fertility and litter numbers. Manganese is required for progesterone production, while iron and chromium are required for further hormone activity, which influences embryo survival during pregnancy. Uterine capacity, which dictates the number of piglets born, requires appropriate feeding levels of selenium, iron and chromium.

Breeding animals have higher mineral requirements, since they must produce ova that are robust enough to achieve conception, supply developing fetuses with minerals for correct development and, in the case of mammals, produce milk to suckle their young. As such, breeding sows can often be deficient in mineral intake, especially when tissue reserves are depleted.

Dr. Pickard further delves into the different roles minerals play in supporting optimum sow performance and the difference the right mineral can make to your sows and her piglets. To find out more, read the rest of Dr. Pickard’s article.

I want to learn more about nutrition for my pig herd.

Dietary trace minerals like copper, zinc and manganese are nutrients critical to animal health, performance and welfare. Immunity, reproduction, growth and even meat and milk quality hinge on optimal trace mineral nutrition.

Everything we know about trace mineral nutrition, from inclusion levels to effects on performance, has come from studies using inorganic trace mineral salts. Trace mineral salts are made from a trace mineral loosely bound to a charged ion and have been the basis of trace mineral supplementation and research since the 1930s. Recent studies, however, are using a different form of trace mineral, and the results of those studies are challenging ideas once considered fundamental to livestock nutrition.

In the early 1990s, organic trace minerals were first developed to reflect the way trace minerals naturally occur in plants. These supplements have a protein-like or carbohydrate ring structure that attaches to the trace mineral at multiple sites. The protein or carbohydrate component serves as a protective, stable delivery system, increasing the likelihood of mineral absorption.

The last 20 years of research confirm that the difference between a mineral salt and a trace mineral bound to a stable organic ring are substantial. The evidence points to organics as a superior source of trace minerals, but beyond that, we see unprecedented effects in the animal when they receive optimally formulated minerals. Organic trace minerals are changing the way we look at livestock nutrition overall.

Below are seven major changes to nutritional dogma instigated by studies looking at organic trace minerals. While many nutritionists still cling to the low-priced, traditional inorganics, organic trace minerals are fostering a revolution in animal feeding.   

1. Not all trace mineral forms are created equal

Historically, inorganic trace minerals have been the primary form of mineral supplementation. Their inexpensive synthesis, however, produces a supplement that quickly dissociates and reacts within the feed and digestive tract.

Dr. Richard Murphy is a biochemist and research director in Dunboyne, Ireland, who has focused much of his work on characterizing, comparing and optimizing trace mineral supplements.

"When comparing mineral products — both inorganic and organic — the key differentiation point is to understand their stability through the GI tract," said Murphy. "Stability at the acidic pH found in the gastric environment is critical to ensuring maximal delivery of mineral to sites of mineral absorption in the intestine."

Dr. Murphy's work has repeatedly shown that organic trace minerals are far superior to traditional inorganic trace minerals in both stability and overall bioavailability. They are, in fact, so much more efficient that countless animal trials have shown that organic trace minerals can be fed at significantly lower levels than their inorganic counterpart without disrupting health and performance. 

Surprisingly, Dr. Murphy's research has also found that not all organic trace minerals are created equal.

"Ultimately, the type and position of the amino acids used in organic trace minerals are critical for stability," said Dr. Murphy.

Different brands of organic trace minerals use different amino acid and peptide strands, some with far weaker associations and lower stability than others.

Dr. Murphy and his research associates have developed a peptide-trace mineral configuration for use in organic trace minerals that provides optimal stability. It is, in fact, his work in differentiating organic and inorganic trace minerals that has laid the foundation for the six other breakthroughs in mineral nutrition.

2. Inorganics: Not required

The National Academies of Sciences, Engineering, and Medicine (NASEM) publishes livestock requirements for all essential nutrients, among which it lists inorganic trace minerals. New research, however, proves that, while trace minerals are essential, there is no absolute requirement for inorganic trace minerals. In fact, eliminating inorganics altogether and replacing them with organic trace minerals appears to enhance performance. 

In beef cattle, a total replacement of inorganic trace minerals with lower levels (60 percent) of organic trace minerals improved health and performance and generated a $50/head advantage (Holder et al., 2016). Total replacement with organic trace minerals in pigs improved average daily gain, increased slaughter weight by 2 kg and improved slaughter efficiency to generate a savings of $1.80 per pig.

Inorganics may prevent deficiency, but there are far more effective supplement options. Even operations feeding a combination of inorganic and organic trace minerals stand to benefit from converting to 100 percent organic trace minerals. The total replacement of inorganics offers the best results in achieving animal genetic potential.

3. Organic trace mineral bioavailability: using less to do more

Studies routinely feed organic trace minerals at levels 30-50 percent lower than inorganics because the superior delivery system of organics allows them to be more efficiently absorbed. Poultry scientists at the University of Kentucky asked, "Just how much more efficiently?"

In their study, broilers were fed organic trace minerals at levels 75 percent lower than commercial levels for inorganics. These birds reached a desirable market weight in the standard six-week period and showed no signs of deficiency or disease, even though they were fed only one-quarter the mineral ration of their inorganic-fed counterparts (Ao et al., 2009). These relative concentrations are below those traditionally recognized as needed for meeting the birds’ requirements.

Organic trace minerals are more effectively absorbed and deposited in the intended tissues, so small amounts can have a greater impact. The inefficiency of inorganics requires producers to significantly overfeed them. Organic trace minerals offer a way for producers to maximize resources. This research also gives us a clearer picture of what an animal's true trace mineral requirements might be.

4. Organic trace minerals contribute to significant improvements in animal health

Trace minerals have a lock-and-key effect on certain antioxidant enzymes that are critical to immune function. A sufficient supply of trace minerals can be described as the sustaining fuel of the immune system. Recent feeding trials and nutrigenomic studies showcase organic minerals taking on some of agriculture’s most costly diseases.

In feedlot cattle, a total replacement of inorganic trace minerals with lower levels of organic trace minerals (60 percent of commercial levels for inorganics) was able to reduce mortality by 57 percent and mortality due to bovine respiratory disease (BRD) by 69 percent. Even in the cattle contracting BRD, the number of retreats was significantly reduced with organic trace minerals (Holder et al., 2016). Too good to be true? A separate study conducted on a different continent confirmed the effects: organic trace mineral groups showed a 7.7 percent decrease in even the incidence of BRD (Sgoifo Rossi et al., 2018).

"BRD costs the U.S. beef industry upwards of $800 million and is the greatest concern and cause of loss at the feed yard,” said Dr. Vaughn Holder, lead beef researcher at Alltech. “Organic trace minerals provide a new reinforcement to the animals’ first line of defense and add tremendously to the producer’s peace of mind."

In poultry, necrotic enteritis (NE) brings devastating costs, approaching $6 billion annually with mortality rates of 1 percent per day. Organic trace minerals eliminated bird death due to NE, reducing mortality by 12 percent compared to inorganics (He et al., 2017; Bortoluzzi et al., 2017). Birds on organic trace minerals also showed significant positive changes to the expression of genes related to improved disease resistance.

From gene expression to disease markers and mortality, there is mounting evidence that the bioavailability of organic minerals better equips animals to take on and survive disease challenges.

5. Organic trace minerals lead to extended shelf life and improved meat quality

The impact of organic trace minerals spans the entire food chain, all the way to our own refrigerators. Animal nutrition directly affects meat quality, as feeding organic trace minerals results in meat that lasts longer and tastes juicier.

"Trace minerals are essential to antioxidant enzymes in the meat," said Dr. Rebecca Delles, an Alltech meat scientist. "By providing a trace mineral source that is more bioavailable, those antioxidants have a better mineral supply to sustain their activity."

Proving her point, beef from steers that were fed organic trace minerals showed increased antioxidant activity, which led to extended shelf life (Sgoifo Rossi et al., 2018). That same meat also showed increased water retention, which improves profitability and texture. Dr. Delles found that organic trace minerals had the same effect in pork loin and chicken breast, beneficially improving both sensory experience and the producer’s bottom line (Delles et al., 2014; Delles et al., 2016).

"The average amount of time it takes a consumer to recover from a bad meat purchase is three months,” said Dr. Delles. “If the appearance, flavor or texture is perceived as being low quality, it will be another three months before the customer reconsiders purchasing that meat product. In fresh pork, if only 5 percent of U.S. consumers have a bad meat experience, that could still bring a projected loss of 3 percent — or $181,938,556.80 — over the course of 12 weeks due to what might seem like 'just color or texture.'"

6. More efficient organic trace minerals decrease the environmental impact of livestock

Bioavailable organic trace minerals are the exclusive method of sustaining animal performance while simultaneously lowering environmental impact.

The instability of inorganic minerals makes them difficult for the animal to absorb. This often leads to overfeeding of trace minerals and, therefore, excretion of large quantities of minerals back into the environment. These excreted minerals alter what is known as a “mineral footprint” and contribute to soil and water contamination.

The improved bioavailability allowing lower inclusion rates of organic trace minerals has been found to directly reduce the mineral footprint of livestock.

A series of trials conducted by agriculture institutions across China in 2017 found that in swine, poultry and ruminants, organic trace minerals could be fed at substantially lower quantities than inorganics and yield the same performance — but return much lower mineral excretion. The same was not true for inorganics: while low levels of inorganics also reduced mineral excretion, they were detrimental to animal health and reduced performance (Guo et al., 2017; Ma et al., 2018; Qui et al., 2018).

"This type of research changes the way we study animal nutrition,” said Dr. Karl Dawson, ruminant microbiologist and chief scientific officer at Alltech. “These are the solutions we need to sustainably feed our growing populations — benefitting all stakeholders while decreasing the environmental impact of intensive animal production systems."

7. Optimal organic trace mineral nutrition improves herd health, reproduction and performance for multiple generations

Trace minerals have a multigenerational effect. Like other nutrients, trace minerals change gene expression, effectively turning genes on or off, up or down. Those changes in gene expression are heritable — meaning the effects of a mother's nutrition, good or bad, are passed on to her offspring before they even take their first bite of feed. This phenomenon, known as epigenetics, gives producers and nutritionists the power to use nutrition to build their future herd. 

Dairy scientists at Pennsylvania State University studied a herd over three generations and found that heifer calves experienced 10 fewer days of sickness and came into estrus 26 days sooner when their dams were fed organic trace minerals (Gelsinger et al., 2016; Pino et al., 2018). This was true even for heifer calves who didn't consume organic trace minerals themselves, confirming that the effect was solely due to maternal nutrition. Fewer days of sickness are correlated to increased milk production later in life and reaching reproductive maturity almost one month sooner, which is worth approximately $100/head in management costs and a 2-3 percent decrease in carbon footprint.

In beef cattle, calves born to cows fed organic trace minerals showed improved body weight through weaning and again at 205 days, regardless of their own diet (Price et al., 2017). Weaning is one of the most critical stress points in the beef life cycle — but organic trace minerals in utero allowed weaning and young calves to thrive despite their circumstances. While trace minerals can have an incredible impact on a single animal, results like these show potential for strategized feeding for the future herd.

The advent of precision feeding

From feed to fork, trace mineral source makes all the difference. Organic trace minerals provide livestock with an essential nutrient in an optimized form, and the effects of such precision reverberate throughout the entire food chain. With effects on animal health and welfare, producer livelihood, consumer preference and environmental protection, no stakeholder is overlooked. This is the advent of a revolution in precision feeding. Well-timed, optimally designed nutrients can reveal to us an animal's real requirements and allow them to achieve their true genetic potential, so that we can build better herds and feed a growing population.

Click here to learn more about solutions through the Alltech Mineral Management program. 

Citations

Holder, V. B., Jennings, J. S., Covey, T. L. (2016). Effect of total replacement of trace minerals with Bioplex® proteinated minerals on the health and performance of lightweight, high-risk feedlot cattle, Journal of Animal Science, 94 (5), 120

Taylor-Pickard, J., Nollet, L., and Geers, R. (2013). Performance, carcass characteristics and economic benefits of total replacement of inorganic minerals by organic forms in growing pig diets, J. Appl. Anim. Nutr. 2 (e3): 1-3

T Ao, JL Pierce, AJ Pescatore, AC Cantor, KA Dawson & MJ Ford. (2009). Effects of feeding reduced levels of organic minerals (Bioplex) on the development of white layer pullets, Poult. Sci. 88 (Suppl. 1), 197

Sgoifo Rossi, C.A., Ripamonti, G., and Compiani, R. (2018, May). Not all mineral supplements for beef cattle bring same results. Feedstuffs, 90 (5).

He, B., King, W., Graugnard, D., Dawson, K.A., Bortoluzzi, C., Applegate, T. (2017). Zinc source influences the gene expression of zinc transporters in the jejunum and cecal tonsils of broilers challenged with coccidia and Clostridium perfringens., Poultry Science Association Annual Meeting, Orlando, FL, USA, 17-23 July, 2017

Bortoluzzi, C., Lumpkins, B., Mathis, G., King, W.D., Graugnard, D., Dawson, K.A., Applegate, T. Comparative efficacy of dietary zinc sources for the mitigation of the impact of necrotic enteritis in coccidial challenged broiler chickens, Poultry Science Association Annual Meeting, Orlando, FL, USA, 17-23 July, 2017

Delles, R.M., Xiong, Y.L., True, A.D., Ao, T., Dawson, K.A. (2014) Dietary antioxidant supplementation enhances lipid and protein oxidative stability of chicken broiler meat through promotion of antioxidant enzyme activity, Poult. Sci. 93:1561-1570

Delles, R.M.,  Naylor, A., Kocher, A., Dawson, K.A., Samuel, R.S. (2016). Diets with organic trace minerals (Bioplex®) and yeast protein (NuPro®) improved the water-holding capacity of pork loin meat, Midwest Animal Science Meetings, March; J. Animal Sci. 94 (Supple. 2): 65

Guo, Y., Liu, B., Xiong, P., He, J., Gang, L., Xue, Y.,Koontz, A.F., Yu, D. (2017). Effect of Cu Provided As Bioplex® Cu or TBCC for Weaned Pigs, Growth Performance, Tissue Mineral Retention, and Fecal Mineral Excretion, ASAS-CSAS Annual Meeting, 17-20 July, Baltimore, MD, USA, 2017

LX Ma, JN He, CC Hou, JL Qiu, XT Lu, B Liu, G Lin, Y Xue, AF Koontz, DY Yu. (2018). Effect of compound organic trace minerals on growth performance, serum indices and micromineral excretion in fattening pigs, ASAS-CSAS Annual Meeting, 5-8 July, Vancouver, Canada

JL Qui, XT Lu, LX Ma, CC Hou, JN He, B Liu, G Lin, T Ao, DY Yu (2018). Effect of low dose complex organic trace minerals on productive performance, egg quality and fecal mineral excretion of laying hens, Poult. Sci. 97 (e-Suppl. 1): 202

Price, D.M., Arellano, K.K., Irsik, M., Rae, D.O., Yelich, J.V., Mjoun, K., Hersom, M.J., (2017) Professional Animal Scientist 33: 194–204

Gelsinger et al., 2016 Maternal and early life nutrition and calf health

Pino et al., 2017 Maternal and early life nutrition and offspring first lactation

This year at the Cattle Industry Convention & NCBA Trade Show, Alltech sponsored the Mineral Myths Forum, which featured industry representatives and their discussion on the myths behind mineral supplementation. We interviewed two experts who were present at the forum to hear their takeaways from the event.

Mineral quality over quantity

Dr. Vaughn Holder, ruminant research director at Alltech, was interested in the discussion surrounding the levels of minerals in supplements.

“The key point to take away from this forum is that you cannot judge a bag of mineral supplements by its cover,” said Holder. “The fact that a certain bag has higher levels of minerals in it does not mean it should be worth more to your enterprise. It is more about the quality of the components that are inside of the bag, and sometimes you can get away with using much lower levels of quality minerals and actually achieve better results. Remember, sometimes less is more!”

The saying “less is more” is one that we hear often, but not always when it comes to mineral supplementation. Holder emphasizes the fact that some companies focus strictly on quantity of minerals, not necessarily quality. However, in a University of Florida study featuring Alltech’s Bioplex® and Sel-Plex® organic trace minerals, it was found that, even when included at lower rates than their inorganic counterparts, Alltech organic trace minerals still managed to outperform the standard mineral in various areas, including weaning weights, pregnancy rates and even colostrum quality. For a full recap of this study, which was featured in the February issue of Progressive Cattleman magazine, click here.

Mineral antagonists

Another point discussed during the forum was the concept of “mineral antagonists,” a complex-sounding topic that is actually very simple — something that blocks or decreases the absorption rate or metabolic function of a nutrient. We pulled in Mark Robbins, manager of research and technical services at Ridley Block Operations (the makers of CRYSTALYX®), to speak on the issue.

“If you have mineral antagonists, which is where you have situations in which inorganic trace minerals aren’t your best option, the Blueprint® program that we have formulated with Total Replacement Technology™ using organic trace minerals is the way to go,” he said. Research has shown that certain organic trace mineral complexes resemble those found naturally in plant proteins, and this may be the reason that they do not act as antagonists in the ration.

We hope you enjoyed the Cattle Industry Convention & NCBA Trade Show as much as we did this year, and if you didn’t get a chance to attend, visit our Facebook page for recaps of the event. We hope to see you next year in New Orleans, Louisiana!

Panelists Dr. Vaughn Holder, Dr. Tanya Covey, Mark Robbins and Dr. Matt Hersom at the Alltech Mineral Myths Forum during the 2018 NCBA conference. 

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Every producer knows that when a beef cow is healthy, her calf has a much better chance of being healthy, too. Trace mineral nutrition is key for maintaining healthy cattle at all life stages. Colostrum quality, calf weight and immune function are among the many benefits from supplementing organic trace minerals in cattle. A study done in 2017 at the University of Florida and published in The Professional Animal Scientist evaluated the response of 160 Angus (AN) and Brangus (BN) cows and their calves to inorganic (ING) or organic (ORG) trace mineral sources.

About the study

The purpose of the study was to evaluate the difference in performance and benefits provided by feeding organic trace minerals versus inorganic trace minerals to cattle on pasture. Beef cows supplemented with organic trace minerals received cobalt, copper, manganese and zinc in the form of Bioplex^® and selenium in the form of Sel-Plex^®. Beef cows supplemented with inorganic trace mineral products received them as sulfates and sodium selenite, respectively.

The level of mineral supplementation also varied between treatment groups:

• In the pelleted feed, the organic trace mineral treatment included 25% less copper, 13% less manganese and 29% less zinc compared to the inorganic trace mineral treatment.
• In the free-choice mineral, the organic trace mineral treatment included 45% less copper, 32% less manganese and 46% less zinc than the inorganic trace mineral treatment.

The best mineral strategy for cattle is one that fits within the producer’s operation, based on their animal requirements and budget and the benefits provided from that mineral product. Organic trace minerals, such as Bioplex and Sel-Plex, are more bioavailable and, as a result, can be added at much lower inclusion rates than the traditional inorganic sources, which not only benefits the environment but, ultimately, the health, well-being, reproductive performance and growth of the animals as well.

Effects of trace mineral source on colostrum

The University of Florida trial revealed that colostrum from lactating cows supplemented with organic trace mineral supplement sources contained 29% more immunoglobulin M (IgM mg/dL) antibodies compared to cows supplemented with inorganic trace minerals (P= 0.07). Cows supplemented with the organic trace mineral sources Bioplex and Sel-Plex also demonstrated significantly higher levels of selenium measured in colostrum —and Angus cows specifically had twice as much selenium compared to their inorganic counterparts (P ≤ 0.001).

The study results also showed that the somatic cell counts (SCC) of the colostrum from Angus cows fed organic trace minerals were 67% lower than the SCC of the colostrum from cows fed inorganic trace minerals. Additionally, Brangus cows fed organic trace minerals had 14.6% lower SCC compared to cows fed inorganic trace minerals.

Effects of maternal mineral nutrition on calf weight and antibody levels

As the study progressed, the researchers at the University of Florida observed that calves from cows fed the organic trace mineral sources (Bioplex and Sel-Plex) showed a statistically significant increase in their average daily gains, weaning weights and 205-day adjusted body weights compared to calves fed inorganic trace mineral sources (P ≤ 0.01).

Calves from cows who were supplemented with Bioplex- and Sel-Plex- had 205-day adjusted body weights that were, on average, 22 pounds heavier compared to the weights of calves from cows that were provided with inorganic sources (P ≤ 0.01). Specifically, Angus calves supplemented with Bioplex and Sel-Plex minerals were 33 pounds heavier (205-day adjusted weaning weights) compared to calves from Angus cows supplemented with inorganic trace mineral sources.

The researchers also measured immunoglobulin levels and found that the immunoglobulin A (IgA mg/dL) antibody measurements for calves from cows supplemented with organic trace minerals Bioplex and Sel-Plex demonstrated a statistically significant (40.5%) increase in calf serum 24 hours after colostrum consumption compared to calves from cows provided with inorganic trace mineral sources (P = 0.04).

Bioplex^® offers a range of trace minerals that provide mineral nutrition in a form as close to nature as possible. Bioplex minerals are trace minerals that are bound to amino acids and a range of peptides. They are easily absorbed and readily metabolized, optimizing animal performance. Bioplex trace minerals (including zinc, manganese, copper, iron and cobalt*) are co-factors in the enzymes that are critical for the animal’s defense system, growth and reproduction. Learn more about Bioplex here.

Sel-Plex^® is Alltech’s proprietary organic form of selenium yeast. It is an excellent dietary source of selenium and is manufactured to mimic the selenium found in nature. The selenium in Sel-Plex is safer and better able to meet the higher requirements of livestock raised for rapid growth, reproductive performance and health. Learn more about Sel-Plex here.

I want to learn more about nutrition for my beef cattle.

Every year when the calendar flips to May 5, the world joins in Mexico's "Cinco de Mayo" celebration of its historic victory over the mighty French forces. In a David and Goliath battle against an army nearly three times its size, soldiers outside the city of Puebla vanquished the invaders in 1862, turning the tide on a military machine that had been undefeated for nearly 50 years.

France may have looked better on paper, but Mexico had a secret weapon that was far more powerful: sheer determination. Outnumbered but not outmaneuvered, Mexico showed the world that with the proper mindset, ambition can trump ammunition.

While the military victory it commemorates took place over 150 years ago, the spirit of the battle of Puebla lives on. Nowhere is that more evident than in Serdan, located in the same state just an hour’s drive from the battleground site. There sits a beacon of hope that reflects the nation's unflagging resolve to advance economically, technologically and societally: Alltech Serdan.

Alltech's Serdan facility is located about 120 miles southeast of Mexico City. The plant produces two main products: Allzyme ® SSF (a natural enzyme complex that maximizes nutrient release) and De-Odorase® (made from yucca extract, which reduces ammonia from animal waste). The state-of-the-art production facility, which has about 200 employees, is one of the largest facilities of its kind in the world. Construction of a new De-Odorase production facility is underway and is expected to more than double production capacity.

Paul Kilgallen has seen Alltech's investment in Serdan grow exponentially in recent years. The resultant benefits to the community – indeed, to the world – show in the faces of those whose lives they have touched, he said.

"You can't imagine what it feels like to see a young person who never even dreamed of having such an opportunity actually succeed," said Kilgallen, who manages Alltech's plant in Serdan. He has seen that happen many times over through Alltech's internship program, which has resulted in permanent employment for numerous candidates. "You see people here wearing 10-year pins, even 20- and some are close to 25-year. People are seeing that you can build a future at Alltech Serdan," he said.

Because Serdan is largely rural, in the past residents seeking education and employment usually had to move to urban areas, such as Mexico City, to seek career opportunities. Now, more and more residents of Serdan and the surrounding Puebla region are able to stay there after graduation, said Josefina Garcia, who manages Alltech’s community projects in Serdan.

"I'm a local girl, and it means a lot to me to see graduates be able to stay and have a successful career in their own community," she said. "Before, the only stable employment you could find was in the big cities."

Alltech's efforts in Serdan have had a ripple effect worldwide. Kilgallen offered the example of a Haitian student who, while attending the University of Kentucky, met Dr. Pearse Lyons, president and founder of Alltech (which is headquartered in Lexington, Kentucky). Lyons recruited him for a summer internship at Alltech Serdan, where the student was introduced to the company's innovative work with yucca. Afterward the student brought his knowledge and excitement about yucca back to his home country, where it generated interest. Haiti, still recovering from the massive earthquake of 2010, began exploring yucca as a means to improve its agriculture base and economy.

One of the team's most important projects is planting yucca trees throughout the region, which testifies to Alltech's commitment to sustainability. Alltech's operations in Serdan have received numerous awards for sustainability work from the governing authorities in Ciudad Serdan and in the city of Perote in the Veracruz region.

Yucca trees at Alltech Serdan, Mexico. Background: Pico De Orizaba, highest mountain (Volcano) in Mexico

Kilgallen said there are about 60,000-70,000 yucca seedlings at the Serdan facility, which are replanted in the surrounding regions until they reach full growth. About 15 years after planting, the plants are harvested and transported to Serdan, where the yucca logs are used to produce De-Odorase – always with an eye on sustainability. As Kilgallen noted, "For every tree we harvest, we replant three yucca trees."

Alltech's interns, supervised by experienced employees, are currently working on yucca products for an organic certification project. In addition, Alltech's alignment with new yucca suppliers has generated job opportunities, with about 40 new hires by a supplier in Perote.

"You can drive around and see Serdan prospering," said Kilgallen, who over the past several years has witnessed the area bloom into a commercially viable community with a higher standard of living than before.

"We even have Walmart-type stores now,” he added. "You don't see that in towns comparable to Serdan. The improvements on employees' quality of life are clear, even as exemplified by the types of cars now in the facility’s parking lot."

And, their success is paid forward. Some of Alltech's new and ongoing community projects in Serdan include aid to schools for disadvantaged and disabled children, including donations of computers and classroom furniture, as well as upgrades to buildings and play yards. Garcia and her team also help sell products made by students to raise additional funds for the schools. In addition, they make food and clothing donations to the regional prison.

El Cerrito Elementary School, supported by Alltech Serdan

When it comes to your animals’ mineral diet, you’ve likely never been thinking about “Star Wars” but just like the characters of the epic movie series, you have a choice to make. Do you go with organic trace minerals, or do you turn to the dark side: inorganics?

It should be an easy choice, but many get led astray by practices that date back over a decade-and-a-half. If you were to look at how many times the human food pyramid has been updated since then, you would see constant improvement. Likewise, how can we keep our animals’ diets in pace with this constant development of nutritional innovation? It starts with choosing a side when it comes to your minerals.

Choose the side with less mineral waste

To examine an animal’s diet, you often have to look at what is coming out the other end. If the animal’s waste has undigested feed in it, that signals two possibilities: One, the diet is over-fortified with an ingredient; or two, the animal is having trouble digesting the ingredient. Recent studies have shown that grow-finish pigs fed a diet with the total replacement of inorganics with organic minerals had reduced fecal manganese, copper and selenium excretion (Alltech-Zhejiang University Animal Nutrition and Feed Science Research Alliance). Another study looking at supplementing organic trace minerals at 0, 50 or 100 percent of the National Research Council (NRC) recommendations showed that nursery pigs and finishing pigs’ trace mineral requirements did not appear to need dietary trace mineral supplementation at the levels recommended by NRC. This research highlights the fact that organic minerals are better absorbed, stored and utilized by the animal. The more that is absorbed by the animal means less waste reaches the environment and less is wasted from the producer’s pocket book.

Choose the side you can trust

Not all minerals are made the same. Inorganics have an added level of contamination risk for both feed and food. This comes in the form of dioxins, PCBs and heavy metals. In the 2015 Asia-Pacific Heavy Metal Survey, where 498 mineral samples were tested, the trend for heavy metal contamination over the past five years showed an average of 19.4 percent. This contamination figure should be scary for producers, as that leads to an increased risk of immune suppression, liver/kidney damage, decreased growth and even contamination of the tissue. It is important to know where your minerals are coming from and that they are being tested to ensure safety for your animals and the food chain. Alltech’s Q+ (Quality Plus) process is a positive release program that guarantees all incoming batches of raw material sources and final product batches are tested for dioxins, PCBs and heavy metals prior to sale, providing a safe and traceable product that producers can trust.

Choose the side that’s better for your pigs’ health and performance

Minerals are an important part of the pig’s diet, but they are not meant to be just another ingredient. Effective mineral nutrition can have a very significant on health and performance. Organic trace minerals have shown to support the number of pigs born (The Ohio State University). That means a lot for producers looking to reduce overall production costs per pig. In addition to reducing costs, another major concern is the health of the pig. Additional studies have shown that trace minerals supplementation supports healthy antioxidant status. This allows the pigs that the producer has invested in to be healthier and more likely to make it to market (Alltech-Zhejiang University Animal Nutrition and Feed Science Research Alliance).

Don’t be lured to the dark side. Learn more about the Alltech^® Mineral Management program at alltech.com/pig.

I want to learn more about nutrition for my pig herd.