Dr. Aoife Lyons on DHA, Brain Development and Recent Research

Alltech's Dr. Aoife Lyons is a licensed clinical psychologist specializing in children, brain development and ADHD. In this interview, she discussed with David Butler the importance of docosahexaenoic acid, or DHA, and its role in brain function and development. Dr. Lyons highlighted some of the exciting new research that is being done to examine the connection between DHA, sleep quality and attention span in children. We also discussed the pros and cons of fish oil versus algae as a source of DHA.

A transcript of the interview follows:

This is David Butler for Alltech, and I’m here with Dr. Aoife Lyons. Can you tell us a little bit about your background, please?

I’m a licensed clinical psychologist, and my specialty is in children and brain development. I ran a children’s clinic in Chicago for about 14 years where we saw all sorts of children. Many had Attention Deficit Disorder, which is more commonly known as ADHD, and we saw a lot of learning disabilities as well.

How long have you been with Alltech?

I have been with Alltech as a consultant for about 12 years, full-time now for about two years.

Very good. Tell us a little about omega-3 fatty acids and why they are important.

Well, DHA, or those fatty acids that you are talking about, are really, really important to support central nervous systems. Your central nervous system is in charge of your brain. It’s in charge of executive functioning, which is things like time management, being able to organize your time, being able to prioritize, having impulse control, things like this. It’s very, very important in children to have DHA to support that brain development, which is happening so rapidly. Also, it’s really important to have DHA through the lifetime, in particular in old age. There is a lot of literature out there that shows supplementation with DHA helps support memory function in patients with Alzheimer’s.

So, you talk about DHA and omega-3’s. I think it can be kind of confusing for people when they are looking for supplements and thinking about their diet. What is the difference?

Oftentimes when you go to Whole Foods or another health food store, you will see omega-3 fatty acids, and those are coming from fish oil, but when we think about where did the fish get their oil to begin with, it’s from algae. The more pure form of DHA would be from that algae. Alltech has several algae facilities that we’re developing at this point and lots of different uses that we are hoping for. My interest, of course, is in the cognitive development of children. I thought, wow, Alltech is doing this research with DHA and algae, how can we bridge the gap between what Alltech offers scientifically and what my personal interests are, which is in the health of children.

There is a lot of research into the importance of DHA, of course, and I’m sure that you have read several studies on it. What are the current focus areas, and what are some of the results?

Interestingly enough, most of the studies have been in 2012 and 2013, so this is really a cutting edge in terms of scientific research, into psychology and interbrain development. One study did supplementation through about 300 mg of DHA in children for 16 weeks, and then they asked the parents and the teachers, before and after, to rate the children on different behaviors, such as impulsivity, concentration, attention, these sorts of things. They did see improvement in children after the 16 weeks of supplementation.

What is more interesting is that for children with learning disabilities, it seems like the effects of DHA are greater than just more typically developing children. People say, why is this? Again, this is really cutting-edge research. It’s all very very new. There is one interesting study, I believe it was in 2013, that looked at children’s sleep cycles and children with ADHD in particular. They found for all children, supplementation with the DHA for this 16-week cycle, they hooked them up to sleep machines and the whole thing, and what they found is that children were getting on average 57-58 more minutes of sleep per night. Now, this does not mean that the children were in bed for almost an hour more per night. It just meant that they had less episodes of waking up during the night. And then they looked at the children’s attention after the supplementation, and they found that the attention and also their academic skills had improved.

Sometimes people will say to me, of course academic skills are going to improve after about four months, of course we’re going to expect reading to be better, and I think something that most people wouldn’t realize is that the tests that we give children, the psychological and academic tests, they are normed to the month so that children who are 7 years, 1 month old, would be compared to children who are 7 years, 1 month. So a child then who is 7 years, 5 months, is compared to other children of the exact same age. So, when we see improvement in reading, it is a true improvement.

That sounds like a pretty dramatic difference. Almost an hour of extra quality sleep, and I’m sure anybody that has kids knows that they're easier to get along with if they have better sleep. So what is the next step?

Well, again, this is very new research, and a lot of the studies that have been done were done in England. There hasn’t been a lot of literature coming out of the US yet. Small-scale studies, specific to schools or to clinical groups, maybe in a pediatrician’s clinic. What we need are larger-scale studies so we can piece out what exactly is going on with the DHA supplementation and the improved academics and the improved attention. I think that increased knowledge in the public about the benefits of DHA, exactly what it does in the brain to support the central nervous system development, is really important.

You know, when you think about it, we’re saying fish oil, and it could have easily been called snake oil many years ago. So I think educating the public is important, so that they are more on board in terms of having their children take part in these sorts of studies. I know for myself, I am taking the fish oil. I know whenever I had researchers Becky Timmons, she takes a lot of fish oil. Her daughter also took fish oil when she was studying for her law school exams.

So I think the larger-scale studies will be important, and I would love to see cross-cultural studies. I would love to see if children, say, in Japan, where the diet is more heavily based on fish, see if those children have better attention and concentration than the U.S. children, and is that due to their diet, or is that due to the cultural reasons and expectations that parents have for their child’s behavior?

Do you have any plans for your own research coming up?

Well, I do, actually. I would love to do another study. A lot of those studies that have been done have been using omega-3 fish oil. I would love to do a study that is just looking at the DHA, just at the algae. We have plans that are underway. We are just in the very early stages at this point. I would love to do a larger scale study with DHA from algae supplementation in a bigger group of school children with the same model as some of the other studies that have been done, but a bigger group of children so we can piece out, does this work for all children? Does this work with kids with ADHD? Does it work better with kids with learning disabilities? So there is a lot of research that can be done. I’m to the point where I have found a couple of schools that are interested in this project, but it wouldn’t get underway until probably a year from now.

Let’s suppose that you have two routes for supplementing the DHA and you could either take fish oil or you could take algae. If you had an equal quantity of DHA either way, would there still be advantages to algae? Why would that be preferable over fish oil?

Well, in terms of doing research with children, there are all sorts of methodological things that you have to think about. Taking the fish oil capsules is not exactly a pleasant thing, sometimes if you haven’t had breakfast it can make you feel a little sick to your stomach, but we do know that there are some gummy bear algae based DHA products available out there, so that would be one way to go. Try to make it a treat for the kid.

If we’re trying to increase the number of people that are improving their diet with DHA, would algae or fish oil be more sustainable method for that?

It’s a lot more sustainable to grow a lot of algae than it is to grow the algae to feed the fish to farm the fish. It’s kind of just going to the source instead of taking it one more step.

And it also doesn’t taste like fish.

Correct.

Thank you very much, and good luck with your research. I hope we have the chance to talk to you about that soon.